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T-cell engager / Hematology/oncologymutCALR-driven myeloproliferative neoplasmsPreclinical / IND-enablingIND or CTA submission planned 2027USex-US 3assets quaratusugene ozeplasmid (REQORSA)REQORSA / TUSC2 / non-viral gene therapy / OncologyEGFR-mutant NSCLC (osimertinib-resistant)Phase 1/2Phase 2a expansion enrollingUnited Statesextensive-stage SCLC (maintenance with atezolizumab)Phase 1/2expansion enrollingUnited States GPX-002GPX-002 / PDX1 and MafA / AAV gene therapy / DiabetesType 1 DiabetesPreclinicalType 2 DiabetesPreclinical NPRL2 gene therapyNPRL2 / non-viral gene therapy / OncologyKRAS/STK11 mutant anti-PD1-resistant NSCLCPreclinical 3assets HLP0035-HT2A (and other serotonin receptors) / Deuterated NSA (oral) / Mental HealthAdjunctive treatment of major depressive disorder (MDD)Phase 3Dosing underway (PARADIGM program)

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