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Guttides are a blend of gastrointestinal-focused peptides, specifically BPC-157 and KPV, recognized for their unique benefits in promoting gut health through anti-inflammatory actions and protective effects

Exclusion criteria included studies evaluating other substance use disorders, carnitine and mood disorders, nonEnglish studies, studies conducted in cell lines or rodent studies and conference abstracts

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Dopamine signaling pathways and LRRK2 gene mutations can exacerbate mitochondrial dysfunction by interfering with H 2 O 2 /O regulatory mechanisms, further impairing the plasticity and survival of NSCs [289, 290]