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10.1016/j.jsbmb.2016.04.007 J

Because a major physiologic function of GSH is to provide cells with a reducing environment and to destroy the reactive oxygen compounds and free radicals formed in metabolism, organs that have low concentrations of other antioxidants (such as catalase and superoxide dismutase) are thought to be more dependent on GSH for detoxification of reactive oxygen species than are organs that have alternative antioxidants

Proline biosynthesis is a vent for TGF-induced mitochondrial redox stress

As a result, greater weight loss is achieved over time, as more calories are burned than with standard dietary restrictions or exercise alone