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Notably, 17 human proteins were upregulated in the defense response to bacterium, including C4BPA, RNASE3, CTSG, MMP9, RETN, AZU1, EPX, MPO, ELANE, SERPINB4, PRTN3, LCN2, CRP, S100A9, S100A8, HNRNPA0, DEFA3, APCS, FGA, NT5C3A, HRG, F12, LTF, FGB, FGG, RTN4R, C1QA, C5, CFP, TTN, IGHG2, A2M, TF, PPP1CB, and CFH