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Protective effect of Piper longum Linn

Yao Y, Walsh WJ, McGinnis WR, Pratic D

This particular antioxidant seemingly made headlines for its benefits during the COVID-19 pandemic

We further show that overexpression of enzymes or supplementation of key metabolites in the transsulfuration pathway of SAA metabolism significantly restores the sensitivity of HNF4-depleted liver cancer cells to methionine/cystine restriction or sorafenib treatment and inhibits cell migration (Fig