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For mild to high-risk procedures or if the last GLP-1 dose was within days, consider rapid-sequence induction, use of cricoid pressure where appropriate, or endotracheal intubation rather than laryngeal mask airway

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Consult a health care practioner prior to use if you have diabetes or taking any medications

November 2025: FDA approved expanded Zepbound (tirzepatide) indication for moderate-to-severe obstructive sleep apnea in adults with obesity, following SURMOUNT-OSA trial data showing 62.8% reduction in apnea-hypopnea index the first drug approval for sleep apnea treatment