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Research has shown that drugs such as atglistatin (131), puerarin (132), nuciferine (133) and formononetin (134) improve the related diseases by inhibiting fat lipolysis through ATGL and HSL (135138), as detailed in Table 2

In this retrospective cohort study of electronic health records (EHRs) from the TriNetX Analytics Network, a global federated health research network of approximately 105.3 million patients from 61 large healthcare organizations in the US, we aimed to assess the associations of semaglutide with both incident and recurrent CUD diagnosis compared to non-GLP-1RA anti-obesity or anti-diabetes medications