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They exert systemic and local anti-inflammatory effects and can directly modulate the progression of atherosclerosis

Beyond its namesake function in sleep induction, current literature suggests DSIP may play a role in modulating the hypothalamic-pituitary-adrenal (HPA) axis, potentially influencing the release of luteinizing hormone (LH) and somatotropin

Some insurers now cover Wegovy specifically for cardiovascular risk reduction in patients with established heart disease and obesity, even when their weight-loss-only formulary excludes it

This article examines the mechanism of GLP-1 agonists, their potential risks in Crohn's disease, practical management strategies, and alternative weight management options for patients with inflammatory bowel disease