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Finally, the reliance upon fresh peripheral blood mononuclear cells (PBMCs), which we and others have shown to be optimal for MAPPs sensitivity 16 , brings a degree of randomness and difficulty to sample alleles from different geographies that reflect the span of HLA-DRB1 alleles present in diverse patient populations

While corticosteroids may alleviate inflammation, they could interact with ferroptosis inhibitors in unpredictable ways, necessitating careful evaluation of combinatorial effects

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