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Additional important metabolic regulatory enzymes that require flavin as a co-factor include, succinate dehydrogenase (TCA cycle and complex II of oxidative phosphorylation), glycerol-3-phosphate dehydrogenase (involved in the glycerol phosphate shuttle and triglyceride synthesis), and xanthine oxidase involved in purine nucleotide catabolism
This Review discusses the PPP in mammals, covering its roles in biochemistry, physiology and disease
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Accompanying the increase in use of these drugs has been a surge in individuals seeking guidance regarding their side effects, as well as accidental overdoses
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