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Additionally, PT-141 may maintain some affinity for MC1R in the skin, promoting melanin synthesis and contributing to skin pigmentation when administered too frequently and at high doses [4]
EGF stimulates transcription of CaN19 (S100A2) in HaCaT keratinocytes
A total of 200 mg/kg of GSH (available in Japan as Tathion, Yamanouchi Pharmaceutical, Tokyo, Japan) was administered intra-venously to 10 patients before cardiopulmonary bypass surgery, and the influence on postoperative renal dysfunction was compared with 9 other patients undergoing the same procedure without GSH administration
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