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Liraglutide treatment in this model has alleviated cardiometabolic dysregulation and enhanced cardiac function, resulting in reduced cardiac hypertrophy and fibrosis, as well as diminished atrial weight, natriuretic peptide levels, and lung congestion [84]

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50 Consistent with these sex and compartment-dependent effects, our preliminary data showed that an 8-week, 30% CR regimen induced cortical bone loss in both sexes, whereas trabecular bone mass was enhanced in females