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By doing so, apremilast appears to interrupt the production of numerous proinflammatory cytokines, including tumor necrosis factor-alpha (TNF-), that are elevated in psoriasis

Allison, and Joseph El Khoury

10 mg vial + 2 mL BAC water: Concentration = 5,000 mcg/mL (5 mg/mL) 5 mg dose = 100 units (1.0 mL) on a 100-unit insulin syringe 10 mg dose = entire vial (use two 100-unit draws or reconstitute with 1 mL for 10 mg/mL) Doses per vial: 2 doses at 5 mg, or 1 dose at 10 mg Supplies Needed (20-Day Cycle at 5 mg/day) 10 vials Epithalon (10 mg each) provides 20 doses at 5 mg 1 vial bacteriostatic water (30 mL) 20 insulin syringes (2931 gauge, 100-unit) Alcohol prep pads Administration Injection Technique Epithalon is administered via subcutaneous (SubQ) injection

The company went testing-first from the start, contracting MZ Biolabs in Tucson to verify every batch before sale independently