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It may influence metabolism through pathways like AMPK activation, gut microbiome effects, and possibly modest increases in endogenous GLP-1 secretion

B12 works to metabolize homocysteine, an amino acid that at elevated levels is a well-established independent risk factor for heart disease and stroke

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James SJ, Rose S, Melnyk S, Jernigan S, Blossom S, Pavliv O, Gaylor DW: Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism