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Description

HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis

Leukemia (2022) 36(8):200921

however, these results also highlight the need for future improvements to maintain structural diversity at larger generation scales

In the 48-week Phase 2 MASH trial (NCT04771273) published in the New England Journal of Medicine, histologic improvement in MASH without worsening of fibrosis occurred in up to 62% of survodutide-treated participants (at 4.8 mg) versus 14% on placebo, with a significant dose-response