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Yafi FA, Pinsky MR, Stewart C, Sangkum P, Ates E, Trost LW, et al

Weight loss of 7-10% of body weight is the most effective treatment for fatty liver disease, achieved through reduced calorie intake and increased physical activity

Recent studies indicate that central GIPR activation reduces body weight by suppressing food intake, whereas peripheral activation promotes weight loss via non-intake mechanisms 26

The FDA gave pharmacies and compounding facilities 60 and 90 days, respectively, from the end of each shortage to wind down operations and for patients to switch to the FDA-approved brand products that were no longer in shortage