If you already take GLP-1 at the time of surgery, your prescribing physician should coordinate with your bariatric surgical team to adjust or pause the medication during the immediate post-operative recovery window
Co-immunoprecipitaton 48 h post transfection, cells were washed by PBS and collected into lysis buffer (Beyotime, P0013) with PMSF (Roche, 10837091001) and protease inhibitor (Merck, 539134) freshly added
With the first oral GLP-1 drug hitting the market in late 2025, a whole new group of people who dont want injections will show up for care
Contributing factors to age-related decline: Reduced GHRH secretion Increased somatostatin tone Decreased GHSR sensitivity Altered sleep architecture (less deep sleep) Increased adiposity (fat suppresses GH) Consequences of GH Decline The somatopause correlates with many aging-associated changes: Research Rationale for Secretagogues GH secretagogues are researched as potential approaches to age-related decline because they preserve natural regulation (working with, not against, physiological systems), avoid exogenous GH risks (receptor downregulation, supraphysiological levels), maintain pulsatility (preserve natural secretion patterns), and are potentially saferthough this remains to be proven in long-term studies
