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Melanotan II is structurally and pharmacologically distinct from both the more MC1R-skewed -MSH analog approved for erythropoietic protoporphyria and the MC4R-leaning linear cleavage analog approved for a premenopausal hypoactive disorder neither of which is this compound, and neither of which shares the same CAS registry number, molecular formula, or clinical development history

The second choice of therapy is with non-psychostimulants such as atomoxetine (ATX), which is a selective norepinephrine reuptake inhibitor, guanfacine, and clonidine, which are selective -2 adrenergic receptor agonists [18,19]

Unraveling nets in sepsis: from cellular mechanisms to clinical relevance