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While B12 is found naturally in animal products, many individuals struggle to absorb it effectively through the digestive tract due to age, gastrointestinal issues, or the use of certain medications

These include vitamin B12 deficiency and malabsorption that is caused by the following medical conditions, according to the NIH [1]: Pernicious anemia Tropical sprue Pancreatic insufficiency Surgery in the gastrointestinal tract Certain medications Deficiency in the diet Side effects of B-12 injections Also, according to the NIH, vitamin B-12 injections have some potential side effects, including [1]: Diarrhea Itching Swelling Risk of allergic reaction and anaphylaxis Can Vitamins Aid in Weight Loss

What is solid-phase extraction Solid-phase extraction (SPE) is a sample preparation technique used in various fields such as analytical chemistry, biochemistry, and environmental examination

This outcome results from combined mechanisms of increased fatty acid oxidation and decreased lipogenesis