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This rapid change can trigger musculoskeletal symptoms even as metabolic health improves

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Determining the best optimal window to hold [these medications] to reduce the risk for aspiration and perioperative complications but also allow patients to get the benefits of GLP-1s is a challenge and important to start identifying further. In addition, Heckmann said research should be conducted to identify the optimal duration of GLP-1 therapy before surgery so patients are no longer in a catabolic state, as well as the duration that yields the optimal amount of weight loss to meaningfully lower a patients complication risk

Reality check: Responses to L-Carnitine vary