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Moreover, the 2017 Cell paper revealed FOXO4-DRI was able to lower the cellular senescence induced by chemotherapy treatment Doxorubicin: doxorubicin-induced senescent cells showed an upregulation in FOXO4 foci and FOXO4-DRI potently and selectively lowered the viability of doxorubicin-senescent versus control IMR90

Nitric Oxide (NO) System Modulation: Research indicates that the peptide acts as a modulator of nitric oxide synthesis (Sikiric et al., 2014)

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