glp-1 agonists in development Emerging Trends the of Receptor GLP-1s & Beyond: Understanding Incretin

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The primary source of cystine in GSH synthesis is available through the cystine-glutamate antiporter xCT

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Direct effects on isolated pancreatic cells Study of possible direct effects of GLP-1 on acini began with the discovery of biologically active peptides in Gila monstor venom (33, 34) and the identification of a specific receptor for Exendin-4 on guinea pig isolated pancreatic acini that increased the production of cAMP (93, 94)