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Melanotan II is a cyclic peptide analog of -MSH studied for its ability to bind melanocortin receptors , most notably MC1R (expressed on melanocytes) and MC4R (involved in appetite/behavior signaling)

But like any medical treatment, they work best when undertaken thoughtfully with the guidance of an experienced physician

Journal of Diabetes Investigation 14(6): 767- Pfeifer KJ, Selzer A, Mendez CE, Christopher M Whinney, Barbara Rogers, et al (2021) Preoperative management of endocrine, hormonal, and urologic medications: SPAQI consensus statement

The standard compression injury was followed by physically cracking the skull (blue) with the microsurgical blade to promote a more severe inflammatory reaction