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Sermorelin tends to produce a steady rise in IGF-1 (insulin-like growth factor 1) within the age-appropriate range, improving sleep quality, recovery, and body composition with a low risk of side effects, says Candice Knight, M.D., a longevity-focused board-certified physician in Family and Integrative Medicine

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While these challenges contribute to higher costs and complexity compared to small molecule drugs, solutions continue to emerge that may reduce these barriers over time