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A separate comprehensive review published in May 2026 in Exploratory Research and Hypothesis in Medicine concluded that GLP-1 receptor agonists appear to favorably affect all 12 recognized hallmarks of aging in laboratory and early clinical settings

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[39] defined treatment (exenatide, lixisenatide, semaglutide, dulaglutide, liraglutide, tirzepatide, albiglutide) and control groups based on GLP-1 RA exposure: the treatment group included patients who initiated a GLP-1 RA within 6 months of IIH diagnosis, while the control group consisted of patients who never initiated a GLP-1 RA but were managed with conventional therapies such as acetazolamide, topiramate and furosemide