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McGuire, found that oral semaglutide reduced major adverse cardiovascular events (MACE) to 3.1 events per 100 person-years, compared to 3.7 events in the placebo group a 14% reduction (HR 0.86) over a median follow-up of 49.5 months

Primary care doctors may refer to registered dietitians or behavioral health specialists to optimize nutritional intake and lifestyle modification alongside pharmacotherapy

These options are ideal for patients looking for flexibility while still benefiting from medically guided weight management support

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