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This interval, called perimenopause, is the adaptive reproductive phase, where there begin to be inconsistent oscillations in ovarian estrogen production as the follicles respond to gonadotrophin waves of follicle-stimulating hormone (FSH) [10]

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Other published papers Mossel et al [7] and Yu et al [8] employed two-layer iodixanol gradient (1.04 and 1.08 g/ml) for part of the isolation process in studies on alveolar type I and type II cells

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