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Trulicity (dulaglutide) Approved - A weekly GLP-1 receptor agonist for managing type 2 diabetes that also supports moderate weight loss by regulating appetite and blood sugar

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The GLP-1 released into the body after eating is mostly stored in L cells, or intestinal endocrine cells

In the Phase 3 trials, nausea was reported by approximately 44% of patients on Wegovy (semaglutide 2.4 mg) and approximately 28% of patients on Zepbound (tirzepatide 15 mg) during dose titration, usually mild to moderate and usually improving with time and dose stabilization