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Each model run started from the end of the 48 hr aerosol sampling period

SURMOUNT-1: Weight Loss Without Diabetes SURMOUNT-1 (N=2,539) enrolled adults with obesity but without diabetes, isolating the non-glycemic weight mechanisms [22]

2 Recommended Storage Conditions for RYBELSUS 2 Before First Use After First Use Room Temperature (68 F 77 F) Room Temperature (68 F 77 F) Until expiration date Until expiration date Saxenda can be used as long as the product has not been exposed to temperatures below 36 F or above 86 F

This was a self-administered questionnaire that each participant was asked to complete within first 1 h of wakening in the morning after the study day