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The mechanism enhanced phospholipid turnover and methyl donor availability operates continuously but produces gradual rather than acute effects

The docking simulations were carried out using the Lamarckian Genetic Algorithm with the default docking parameter

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This narrative review synthesizes current preclinical and human evidence on the bidirectional interactions between GLP-1 RAs and the intestinal microbial ecosystem, with particular attention to microbial composition, metabolite production (including short-chain fatty acids and bile acids), intestinal barrier integrity, and inflammatory signaling