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Most adults should consume at least 1,500 calories per day, and prolonged low calorie intake can harm your metabolism (38, Even if you see initial weight loss on this type of diet, its most likely from water loss and youll likely gain the weight back once the diet ends

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N Engl J Med 392(6):612615 Rosenstock J, Frias J, Jastreboff AM, Du Y, Lou J, Gurbuz S, Thomas MK, Hartman ML, Haupt A, Milicevic Z, Coskun T (2023) Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA