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More recently it has become increasingly used as a once-weekly, low-dose treatment of disorders such as psoriasis and rheumatoid arthritis

The effect was very strong, nearly 30% reduction with metformin alone (first line treatment for type 2 diabetes) but an additional 40% with GLP-1 receptor agonists (eg, Wegovy [semaglutide, Novo Nordisk]), and unexpectedly it was effective for all asthma patients, including those with higher or lower BMI, and with all different types of asthma, Chloe I

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Published cosmetic studies typically report endpoints at 8, 12 and 16 weeks, but those are protocol-defined measurements in small studies, not a guarantee of personal outcome