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Opposing this inflammatory axis is the Nrf2Keap1 pathway, the master transcriptional regulator of cellular antioxidant and detoxification programs [6]

Best for patients whose primary goal is injury repair, faster recovery, or reducing chronic pain and inflammation

doi:10.1186/s12933-020-01169-3 Chen K, Li F, Cai H, et al

Besides direct inhibition of mtDNA replication, NRTIs also obstruct base excision repair and proofreading capabilities of polymerase- (Lim and Copeland, 2001