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According to the BMJ study , the average weight regain was 1.76 pounds per month after stopping semaglutide or tirzepatide, says Kushner

[3] [4] The cardiovascular safety profile of semaglutide has been extensively studied, with the SELECT trial (semaglutide 2.4mg in obesity with established cardiovascular disease) and SUSTAIN-6 trial (semaglutide 1.0mg in type 2 diabetes) demonstrating cardiovascular safety

The good news is that these dysesthesia events were generally mild