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BDNF upregulation The most well-documented mechanism of Semax is its ability to upregulate brain-derived neurotrophic factor (BDNF) a protein that plays a central role in neurogenesis, synaptic plasticity, and the formation and maintenance of neural connections

Starobova H, Vetter I (2017) Pathophysiology of chemotherapy-induced peripheral neuropathy

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Collectively, systematic nutritional intervention is expected to become the third major treatment alongside physical and drug therapy, enabling more OA patients to avoid adverse effects caused by repeated drug use and potential risks associated with surgery and prosthesis replacement