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Prolonged UV exposure can induce matrix metalloproteinase-2 (MMP-2) and MMP-9 activation in basement membrane which can lead to collagen types 4 and 6 degradation and accumulation of more elastic fibers in melasma patients (Inomata et al., 2003)

BBC Panorama also obtained emails which it alleges show that Fudge flew to Zurich five days before the 2014 London Marathon after Farahs coach, Alberto Salazar, introduced him to a contact that could obtain batch-tested L-Carnitine in the injectable form needed, which was not obtainable in the UK