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Pooled safety analyses examined patient-level safety data from phase 13 clinical trials in patients with T2DM

Feeding cycle-dependent circulating insulin fluctuation is not a dominant Zeitgeber for mouse peripheral clocks except in the liver: Differences between endogenous and exogenous insulin effects

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In adults with growth hormone receptor deficiency, eight weeks of rhIGF-1 therapy significantly increased whole-body protein synthesis, decreased protein oxidation and increased lean body mass while reducing fat mass, demonstrating enhanced muscle anabolism and nutrient utilization in humans