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Reasons patients give for stopping include reaching a plateau in weight loss, inability to tolerate side effects, or even inability to get the medication due to shortages

Among these participants, males accounted for 129 individuals, constituting 57.1% of the total population

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Combination therapy with gemcitabine further enhanced efficacy, with the mechanism involving increased lipogenic fibroblasts and reduced myofibroblasts to achieve dual-chamber targeting. Ent also attenuates the effects of TGF- and TGF- and antagonizes transcriptional activation (113)