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If you can lift a fold of at least 1 cm, there is enough subcutaneous tissue for a safe injection

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It requires: Neural stimulation originating in the brain Release of nitric oxide within penile endothelial cells Activation of the cGMP pathway Relaxation of smooth muscle in the corpus cavernosum Rapid arterial blood inflow with restricted venous outflow If nitric oxide production declines, blood cannot adequately fill the corpus cavernosum