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For this purpose, we treated normal aging mice with intraperitoneal injection of FOXO4-DRI at a dose of 5 mg/kg for 1 month

Upregulation of GGT activity is primarily dependent on the Ras protein and its downstream effectors, which include extracellular signal-regulated kinase 1/2 (ERK1/2), p38 mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase (PI3K)/AKT and c-Jun N-terminal kinase (JNK) signaling pathways (Fig

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Restless legs syndrome interferes with falling asleep or maintaining a deep sleep, making the person feel sleepy, tired and distracted during the day