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Notably, the therapeutic effects of GLP-1RAs on ferroptosis induced by the activation of cGAS-STING pathway were similar to that of the cGAS-STING pathway inhibitor C-176

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Under normal circumstances, the physical barrier of the intestinal epithelium allows small molecule nutrients such as water, electrolytes, and glucose to pass through, while preventing harmful substances such as bacteria, endotoxins, and food antigens from entering the body