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Antioxidant & immune modulation Researched as a bioregulator for markers of oxidative stress and immune function in preclinical models
Cells also export GSSG or form reversible mixed disulphides with protein thiols when redox conditions change
A method for preventing radiation-induced ototoxicity in an individual in need thereof comprising intratympanic administration of a pharmaceutical composition comprising a therapeutic agent selected from a JNK inhibitor, TRPV modulator, an MET channel inhibitor, and an otoprotectant to the individual in need thereof, wherein the pharmaceutical composition is administered prior to onset of radiation therapy, and wherein the composition provides sustained release of the therapeutic agent into the ear for a period of at least 5 days after a single administration
The MTT assay was performed according to the instructions, and absorbance was measured at 490 nm
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