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By shedding 60 pounds in just six months on Mounjaro (tirzepatide) , and later discussing setbacks when he lost access to the drug, he opened a conversation many avoid: obesity as a chronic condition requiring medical care, not just willpower

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Glossary CLBP chronic low back pain CKD chronic kidney disease CNS central nervous system CV cardiovascular CVD cardiovascular disease FDA Food and Drug Administration GLP-1 glucagon-like peptide-1 GLP-1s glucagon-like peptide-1 receptor agonists HF heart failure HTN hypertension MACE major adverse cardiovascular events MASH metabolic dysfunction-associated steatohepatitis OA osteoarthritis OSA obstructive sleep apnea PAD peripheral arterial disease SC subcutaneous SGLT2i sodium-glucose co-transporter 2 inhibitor sNDA supplemental New Drug Application T1DM type 1 diabetes mellitus T2DM type 2 diabetes mellitus U.S