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Diabetic Wound Healing Diabetic wound healing studies in rats using collagen dressings with GHK demonstrated higher glutathione and ascorbic acid levels, better epithelialization, 9-fold increased collagen synthesis in healthy rats, and activation of fibroblasts and mast cells
It can effectively scavenge excessive reactive oxygen free radicals in the body, protect the normal structure and function of cells and mitochondria, and prevent the occurrence of lipid peroxidation, thus playing a role in preventing cognitive dysfunction in diabetes (113)
The fusion peptide demonstrated sleep-promoting effects, influenced neurotransmitter levels (5-HT, glutamate, dopamine, melatonin), and confirmed that the Tat cell-penetrating sequence was the more effective BBB carrier of two tested candidates establishing DSIP as a validated active scaffold for BBB-crossing fusion peptide sleep research and supporting the development of next-generation DSIP-based neuromodulatory tools
S.Gomez-QuirozL.CoulouarnC.FactorV
