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As expected from previous studies (25), leptin administration significantly reduced food intake and body weight in fasted WT controls (Figure 4, C and E)

There are certainly some marketing strategies Ive seen that are deceptive, Ard said

When Pinto has a patient who asks about weaning off their GLP-1 or spacing out dosing, he is very receptive to the conversation

Ongoing trials aim to clarify: Cardiovascular safety Long-term weight durability Role in prediabetes and non-diabetic populations Comparison to semaglutide and tirzepatide Until then, we continue to emphasize current best practices: lifestyle support, personalized nutrition, advanced lipid testing, and thoughtful pharmacotherapy