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Description

International Conference on Harmonisation (ICH)

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Gallwitz et al., (1993) proved an additive effect of GIP and GLP-1 on cyclic AMP production in RINm5F insulinoma cells (rat -cells), demonstrating that the adenylate cyclase was influenced by signals produced from both receptors [93]

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However, incretin mimetic therapy is accompanied by a loss of lean body mass that accounts for approximately 2540% of total weight loss 4

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Rare allergic reactions such as hives or facial swelling can occur

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