[21] For patients undergoing surgery , the approach should be individualised based on several factors: Aspiration risk assessment : Patients with symptoms of gastroparesis, those on high doses, or those who have recently initiated therapy may have increased risk Type of surgery : Particularly procedures involving the gastrointestinal tract Indication for GLP-1 therapy : Whether for diabetes management or weight loss If GLP-1 medications are temporarily withheld based on individual risk assessment or local policy, patients with diabetes should have a clear plan for glycaemic management, including capillary glucose monitoring and potential bridging therapy, developed in consultation with the diabetes team
Timing-wise, given a short half-life, once-daily or everyotherday dosing is usually more than enough to keep receptor exposure occurring regularly during a loading period
Key details Compounded GLP-1s Semaglutide injections Tirzepatide injections Semaglutide oral tablets, drops, microdose Tirzepatide oral tablets, drops, microdose Branded GLP-1s Rybelsus (oral) Ozempic Mounjaro Wegovy Zepbound Pomegranate focuses on compounded injections plus oral Rybelsus
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