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a positive correlation was evident between the ability to block dimerization and the inhibition of the cellular outcomes of HGF activation

(n=50) found that tesamorelin produced a mean reduction in visceral adipose tissue (VAT) of -34 cm versus a gain of +8 cm on placebo (net treatment effect -42 cm, P=0.005)

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Persistent vascular inflammation is a hallmark of several autoimmune conditions, including SLE (211, 212), where dysregulated immune cell infiltration exacerbates tissue injury and chronic inflammation