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During this phase, prolactin acts synergistically with other endocrine factors and local regulatory mechanisms in mammary glands to orchestrate systemic and tissue-specific metabolic adaptations ( de novo lipogenesis and lipid uptake in adipocytes and augmenting the lipid biosynthetic capacity in mammary epithelial cells ( 3 Clinical challenges Clinical studies have consistently reported the association between hyperprolactinemia and obesity

The elimination strategy targeting senescent cells thus represents a promising area of research in the context of various pathologies, including cancer, cardiovascular, and neurodegenerative diseases, by targeting the very biological foundation of aging

There were no differences between the control and experimental groups during either phase

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