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Their guidance covers proper injection techniques, site rotation, and aftercare tips to help minimize bruising

PMCID: PMC3728035 ) Acknowledgements Figure 1 was created with Biorender.com

GLP-1 microdosing allows these patients to access the metabolic benefits while minimizing gastrointestinal discomfort, fatigue, or other adverse reactions

Tirzepatide (weekly injectable) Dosing frequency: Once weekly, same day each week Half-life: approximately 5 days (120 hours) Peak concentration: 8 to 72 hours after injection Recommended timing approach: The shorter half-life compared to semaglutide means the end-of-week trough is more noticeable